As of this review, an exclusive and official BioEntopic™ Vitamin K Crème website seems to be unavailable. However, BioEntopic™ has its own website, and it lists the product under its skin care category. As per the page devoted to the product, some of the following ingredients are included: Horse Chestnut Extract, DMAE, Olive Leaf Extract, Vitamin C Esters, Tocotrienol (Vitamin E) and Retinol-A.

While we appreciate a skin cream with natural extracts and vitamins, we believe that they may do nothing to reduce varicose and spider veins. It is important to understand first how these imperfections are formed. Varicose and spider veins are formed when the valves in the veins weaken and cannot sustain opposite blood flow pressure. As a result, blood may start flowing backwards, which, in turn, enlarges the veins and makes them visible to the eye.

A common cause of varicose veins formation may be genetic; some of us may be born with weak veins. Another common cause may be hormonal imbalances, like that of Progesterone. Therefore, it seems obvious that the solution may lie in maintaining healthy veins. We doubt that any topical application may really do this.

We appreciate that the manufacturer has its own website, although we would have liked it much better if the product were promoted through an exclusive website. The webpage devoted to the product lists the ingredients; however, detailed information on the effectiveness of the product seems to be missing. We find a quality product will actually be backed by numerous and positive testimonials. Some really good products will also highlight some before and after pictures.

• Is a skin cream containing vitamins and basic extracts

• Product does not have official and exclusive website at this time
• Testimonials and before and after pictures currently unavailable
• Does not contain proven ingredients, like Diosmin 95®
• May not do anything to reduce appearance of varicose and spider veins
• Is not a supplement that may get to work from within

Thus, although we remain open about the effectiveness of the product as a topical cream with moisturizing benefits, we remain unconvinced that it may target the appearance of varicose and spider veins. There already are specialized products on the market with proven ingredients guaranteed to reduce varicose and spider vein formation. Those of us really wishing to get rid of their appearance may prefer to try such a product.

Nevertheless, it may be difficult to search for and choose such a specific product. However, we may use certain techniques to get hold of the best one. First, we believe such supplements will need to have ingredients proven with clinical trials and used by millions. Second, an over-the-counter pharmaceutical quality pill to reduce the appearance of varicose veins should be FDA-approved. Third, the product should be backed by an official and exclusive website that also has numerous testimonials and before and after pictures.